6T7K
Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline
Summary for 6T7K
Entry DOI | 10.2210/pdb6t7k/pdb |
Descriptor | Proline--tRNA ligase, PROLINE, ~{N}-(2,3-dihydro-1~{H}-inden-2-yl)-3-(piperidin-1-ylcarbonylamino)pyrazine-2-carboxamide, ... (5 entities in total) |
Functional Keywords | trna, proline, aminoacyl-trna synthetase, ligase, protein biosynthesis, atp binding |
Biological source | Plasmodium falciparum (isolate 3D7) |
Total number of polymer chains | 1 |
Total formula weight | 60310.91 |
Authors | Johansson, C.,Wang, J.,Tye, M.,Payne, N.C.,Mazitschek, R.,Thompson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U.C.T. (deposition date: 2019-10-22, release date: 2020-11-18, Last modification date: 2024-01-24) |
Primary citation | Johansson, C.,Wang, J.,Tye, M.,Payne, N.C.,Mazitschek, R.,Thompson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U.C.T. Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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