6STZ

Crystal structure of dimethylated RSLex - cucurbituril free form

Summary for 6STZ

Entry DOI	10.2210/pdb6stz/pdb
Descriptor	Fucose-binding lectin protein, beta-D-fructopyranose (3 entities in total)
Functional Keywords	cucurbituril, molecular glue, crystal engineering, sugar binding protein
Biological source	Ralstonia solanacearum
Total number of polymer chains	6
Total formula weight	61248.76
Authors	Guagnini, F.,Engilberge, S.,Crowley, P.B. (deposition date: 2019-09-12, release date: 2020-02-19, Last modification date: 2024-01-24)
Primary citation	Guagnini, F.,Engilberge, S.,Ramberg, K.O.,Perez, J.,Crowley, P.B. Engineered assembly of a protein-cucurbituril biohybrid. Chem.Commun.(Camb.), 56:360-363, 2020 Cited by PubMed Abstract: A crystalline biohybrid with a 4 : 1 protein : cucurbituril mass ratio is presented. This result was achieved by engineering additional cucurbit[7]uril (Q7) binding sites into a β-propeller protein. In contrast to the parent protein, Q7-controlled assembly of the engineered variant occurred in solution, as evidenced by NMR and SAXS measurements. PubMed: 31825399 DOI: 10.1039/c9cc07198a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.14 Å)

Structure validation