6SNC
crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide
Summary for 6SNC
Entry DOI | 10.2210/pdb6snc/pdb |
Descriptor | LNO1 Light Chain, LNO1 Heavy Chain, Envelope glycoprotein gp160, ... (7 entities in total) |
Functional Keywords | gp41, antibody, complex, mper, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 105645.07 |
Authors | Caillat, C.,Pinto, D.,Corti, D.,Fenwick, C.,Pantaleo, G.,Weissenhorn, W. (deposition date: 2019-08-23, release date: 2019-11-06, Last modification date: 2020-07-29) |
Primary citation | Pinto, D.,Fenwick, C.,Caillat, C.,Silacci, C.,Guseva, S.,Dehez, F.,Chipot, C.,Barbieri, S.,Minola, A.,Jarrossay, D.,Tomaras, G.D.,Shen, X.,Riva, A.,Tarkowski, M.,Schwartz, O.,Bruel, T.,Dufloo, J.,Seaman, M.S.,Montefiori, D.C.,Lanzavecchia, A.,Corti, D.,Pantaleo, G.,Weissenhorn, W. Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01. Cell Host Microbe, 26:623-637.e8, 2019 Cited by PubMed: 31653484DOI: 10.1016/j.chom.2019.09.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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