6RY4
PARP15 catalytic domain in complex with 4-(3-carbamoylphenoxy)benzamide.
Summary for 6RY4
Entry DOI | 10.2210/pdb6ry4/pdb |
Descriptor | Protein mono-ADP-ribosyltransferase PARP15, 3-(4-aminocarbonylphenoxy)benzamide, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | inhibitor, mono-adp ribosyltransferase.., protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 45605.21 |
Authors | Murthy, S.N.,Maksimainen, M.M.,Lehtio, L. (deposition date: 2019-06-10, release date: 2020-07-15, Last modification date: 2024-05-29) |
Primary citation | Korn, P.,Classen, A.,Murthy, S.,Guareschi, R.,Maksimainen, M.M.,Lippok, B.E.,Galera-Prat, A.,Sowa, S.T.,Voigt, C.,Rossetti, G.,Lehtio, L.,Bolm, C.,Luscher, B. Evaluation of 3- and 4-Phenoxybenzamides as Selective Inhibitors of the Mono-ADP-Ribosyltransferase PARP10. Chemistryopen, 2021 Cited by PubMed: 34145784DOI: 10.1002/open.202100087 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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