Summary for 6Q38
Entry DOI | 10.2210/pdb6q38/pdb |
Related PRD ID | PRD_002559 |
Descriptor | Casein kinase II subunit alpha, Stapled Peptide, BENZOIC ACID, ... (5 entities in total) |
Functional Keywords | ck2alpha, ck2a, stapled peptides, high concentration screening, selective atp competitive inhibitors, surface entrophy reduction, peptide binding protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 40870.57 |
Authors | Brear, P.,Iegre, J.,Baker, D.,Tan, Y.,Sore, H.,Donovan, D.,Spring, D.,Chandra, V.,Hyvonen, M. (deposition date: 2018-12-03, release date: 2019-04-24, Last modification date: 2024-03-06) |
Primary citation | Iegre, J.,Brear, P.,Baker, D.J.,Tan, Y.S.,Atkinson, E.L.,Sore, H.F.,O' Donovan, D.H.,Verma, C.S.,Hyvonen, M.,Spring, D.R. Efficient development of stable and highly functionalised peptides targeting the CK2 alpha /CK2 beta protein-protein interaction. Chem Sci, 10:5056-5063, 2019 Cited by PubMed: 31183056DOI: 10.1039/c9sc00798a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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