6Q0Q

Crystal structure of Human galectin-3 CRD in complex with Methyl 3-O-(1-{3-O-[1-(b-D-galactopyranosyl)-1,2,3-triazol-4-yl]-methyl-b-D-galactopyranosyl}-1,2,3-triazol-4-yl)-methyl-b-D-galactopyranoside

Summary for 6Q0Q

Entry DOI	10.2210/pdb6q0q/pdb
Descriptor	Galectin-3, CHLORIDE ION, (2~{R},3~{R},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[4-[[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[4-[[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-methoxy-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]-1,2,3-triazol-1-yl]-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]-1,2,3-triazol-1-yl]oxane-3,4,5-triol, ... (4 entities in total)
Functional Keywords	sugar binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	16474.17
Authors	Kishor, C.,Blanchard, H. (deposition date: 2019-08-02, release date: 2020-04-29, Last modification date: 2024-03-13)
Primary citation	Dussouy, C.,Kishor, C.,Lambert, A.,Lamoureux, C.,Blanchard, H.,Grandjean, C. Linear triazole-linked pseudo oligogalactosides as scaffolds for galectin inhibitor development. Chem.Biol.Drug Des., 96:1123-1133, 2020 Cited by PubMed: 32220037 DOI: 10.1111/cbdd.13683 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.98601176315 Å)

Structure validation