6PVC

Structure of human MAIT A-F7 TCR in complex with human MR1-DB28

Summary for 6PVC

• Entry DOI: 10.2210/pdb6pvc/pdb
• Descriptor: Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, Human TCR alpha chain, ... (9 entities in total)
• Functional Keywords: immune system, mait, mr1
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 188820.68

Authors

Awad, W.,Rossjohn, J. (deposition date: 2019-07-20, release date: 2020-04-01, Last modification date: 2023-10-11)

• Primary citation: Salio, M.,Awad, W.,Veerapen, N.,Gonzalez-Lopez, C.,Kulicke, C.,Waithe, D.,Martens, A.W.J.,Lewinsohn, D.M.,Hobrath, J.V.,Cox, L.R.,Rossjohn, J.,Besra, G.S.,Cerundolo, V.; Ligand-dependent downregulation of MR1 cell surface expression.; Proc.Natl.Acad.Sci.USA, 117:10465-10475, 2020; PubMed: 32341160; DOI: 10.1073/pnas.2003136117

Experimental method

X-RAY DIFFRACTION (1.96 Å)