6NZG
Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine
Summary for 6NZG
Entry DOI | 10.2210/pdb6nzg/pdb |
Descriptor | Beta-galactosidase, (1S,2R,3S,4S,5S,6R)-2-amino-3,4,5,6-tetrahydroxycyclohexane-1-carboxylic acid, GLYCEROL, ... (6 entities in total) |
Functional Keywords | glycoside hydrolase family 2, beta-glucuronidase, activity-based probe, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bacteroides uniformis |
Total number of polymer chains | 2 |
Total formula weight | 202003.73 |
Authors | Pellock, S.J.,Jariwala, P.B.,Redinbo, M.R. (deposition date: 2019-02-13, release date: 2019-12-18, Last modification date: 2023-10-11) |
Primary citation | Jariwala, P.B.,Pellock, S.J.,Goldfarb, D.,Cloer, E.W.,Artola, M.,Simpson, J.B.,Bhatt, A.P.,Walton, W.G.,Roberts, L.R.,Major, M.B.,Davies, G.J.,Overkleeft, H.S.,Redinbo, M.R. Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling. Acs Chem.Biol., 15:217-225, 2020 Cited by PubMed: 31774274DOI: 10.1021/acschembio.9b00788 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.43 Å) |
Structure validation
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