6NEA
Human Acetylcholinesterase in complex with reactivator, HLo7
Summary for 6NEA
Entry DOI | 10.2210/pdb6nea/pdb |
Descriptor | Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 121746.94 |
Authors | Bester, S.M.,McGuire, J.,Height, J.J.,Pegan, S.D. (deposition date: 2018-12-17, release date: 2019-06-12, Last modification date: 2023-10-11) |
Primary citation | Hsu, F.L.,Bae, S.Y.,McGuire, J.,Anderson, D.R.,Bester, S.M.,Height, J.J.,Pegan, S.D.,Walz, A.J. Synthesis and Molecular Properties of Nerve Agent Reactivator HLo-7 Dimethanesulfonate. Acs Med.Chem.Lett., 10:761-766, 2019 Cited by PubMed: 31097996DOI: 10.1021/acsmedchemlett.9b00021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.419 Å) |
Structure validation
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