6N4D

The crystal structure of neuramindase from A/canine/IL/11613/2015 (H3N2) influenza virus.

Summary for 6N4D

• Entry DOI: 10.2210/pdb6n4d/pdb
• Descriptor: Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: neuraminidase, canine influenza virus, viral protein
• Biological source: unidentified influenza virus
• Total number of polymer chains: 4
• Total formula weight: 181848.34

Authors

Yang, H.,Stevens, J. (deposition date: 2018-11-19, release date: 2019-01-30, Last modification date: 2024-10-23)

Primary citation

Pulit-Penaloza, J.A.,Simpson, N.,Yang, H.,Creager, H.M.,Jones, J.,Carney, P.,Belser, J.A.,Yang, G.,Chang, J.,Zeng, H.,Thor, S.,Jang, Y.,Killian, M.L.,Jenkins-Moore, M.,Janas-Martindale, A.,Dubovi, E.,Wentworth, D.E.,Stevens, J.,Tumpey, T.M.,Davis, C.T.,Maines, T.R.
Assessment of Molecular, Antigenic, and Pathological Features of Canine Influenza A(H3N2) Viruses That Emerged in the United States.
J. Infect. Dis., 216:S499-S507, 2017

PubMed Abstract: A single subtype of canine influenza virus (CIV), A(H3N8), was circulating in the United States until a new subtype, A(H3N2), was detected in Illinois in spring 2015. Since then, this CIV has caused thousands of infections in dogs in multiple states.

PubMed: 28934454
DOI: 10.1093/infdis/jiw620

Experimental method

X-RAY DIFFRACTION (1.8 Å)