6MJQ

Crystal structure of the mCD1d/xxp (JJ295) /iNKTCR ternary complex

Summary for 6MJQ

Entry DOI	10.2210/pdb6mjq/pdb
Descriptor	T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, chimeric protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-{(2S,3S,4R)-3,4-dihydroxy-1-[(4-O-{[4-(trifluoromethyl)phenyl]methyl}-alpha-D-galactopyranosyl)oxy]octadecan-2-yl}hexacosanamide, ... (12 entities in total)
Functional Keywords	mhc-fold, ig-fold, glycolipid antigen presentation, t cell receptor, immune system, immune system-inhibitor complex, immune system/inhibitor
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	8
Total formula weight	194251.33
Authors	Zajonc, D.M.,Bitra, A.,Janssens, J. (deposition date: 2018-09-21, release date: 2019-01-09, Last modification date: 2023-10-11)
Primary citation	Janssens, J.,Bitra, A.,Wang, J.,Decruy, T.,Venken, K.,van der Eycken, J.,Elewaut, D.,Zajonc, D.M.,van Calenbergh, S. 4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies. ChemMedChem, 14:147-168, 2019 Cited by PubMed: 30556652 DOI: 10.1002/cmdc.201800649 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation