6LQD

Structure of Enterovirus 71 in complex with NLD-22

Summary for 6LQD

• Entry DOI: 10.2210/pdb6lqd/pdb
• EMDB information: 0943
• Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... (5 entities in total)
• Functional Keywords: inhibitor, virus
• Biological source: Human enterovirus 71 (EV71); More
• Total number of polymer chains: 4
• Total formula weight: 94859.92

Authors

Zhang, M.,Sun, Y.,Wang, X.,Guo, Y.,Rao, Z. (deposition date: 2020-01-13, release date: 2020-03-11, Last modification date: 2024-03-27)

• Primary citation: Zhang, M.,Wang, Y.,He, W.,Sun, Y.,Guo, Y.,Zhong, W.,Gao, Q.,Liao, M.,Wang, X.,Cai, Y.,Guo, Y.,Rao, Z.; Design, Synthesis, and Evaluation of Novel Enterovirus 71 Inhibitors as Therapeutic Drug Leads for the Treatment of Human Hand, Foot, and Mouth Disease.; J.Med.Chem., 63:1233-1244, 2020; PubMed: 31939669; DOI: 10.1021/acs.jmedchem.9b01414

Experimental method

ELECTRON MICROSCOPY (3.264 Å)