6LNZ
NMR solution structure of VEGF G-quadruplex bound a non-planar cyclometalated-carbene platinum(II) complex
Summary for 6LNZ
Entry DOI | 10.2210/pdb6lnz/pdb |
Descriptor | DNA (5'-D(*CP*GP*GP*GP*GP*CP*GP*GP*GP*CP*CP*TP*TP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3'), cyclometalated-carbene platinum(II) complex (2 entities in total) |
Functional Keywords | vegf g-quadruplex, solution structure, dna-ligand complex, platinum complex, dna |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 7466.85 |
Authors | |
Primary citation | Zhu, B.C.,He, J.,Liu, W.,Xia, X.Y.,Liu, L.Y.,Liang, B.B.,Yao, H.G.,Liu, B.,Ji, L.N.,Mao, Z.W. Selectivity and Targeting of G-Quadruplex Binders Activated by Adaptive Binding and Controlled by Chemical Kinetics. Angew.Chem.Int.Ed.Engl., 60:15340-15343, 2021 Cited by PubMed: 33899272DOI: 10.1002/anie.202104624 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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