6LGT

Complex structure of HPPD with an inhibitor Y16542

Summary for 6LGT

Entry DOI	10.2210/pdb6lgt/pdb
Descriptor	4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, 3-(2-chlorophenyl)-6-(1,3-dimethyl-5-oxidanyl-pyrazol-4-yl)carbonyl-1,5-dimethyl-quinazoline-2,4-dione, ... (5 entities in total)
Functional Keywords	dioxygenase, inhibitor, complex, oxidoreductase
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Total number of polymer chains	1
Total formula weight	49489.80
Authors	Lin, H.Y.,Yang, W.C.,Yang, G.F. (deposition date: 2019-12-05, release date: 2020-10-14, Last modification date: 2023-11-22)
Primary citation	He, B.,Wu, F.X.,Yu, L.K.,Wu, L.,Chen, Q.,Hao, G.F.,Yang, W.C.,Lin, H.Y.,Yang, G.F. Discovery of Novel Pyrazole-Quinazoline-2,4-dione Hybrids as 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. J.Agric.Food Chem., 68:5059-5067, 2020 Cited by PubMed: 32286826 DOI: 10.1021/acs.jafc.0c00051 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.794 Å)

Structure validation