6LB5

Crystal structure of dimeric RXR-LBD complexed with full agonist NEt-3IB and TIF2 co-activator

Summary for 6LB5

• Entry DOI: 10.2210/pdb6lb5/pdb
• Descriptor: Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, 6-[ethyl-[3-(2-methylpropoxy)-4-propan-2-yl-phenyl]amino]pyridine-3-carboxylic acid, ... (4 entities in total)
• Functional Keywords: nuclear receptor, retinoid x receptor alpha, active form, co-factors, partial agonist, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 58121.24

Authors

Imai, D.,Numoto, N.,Nakano, S.,Kakuta, H.,Ito, N. (deposition date: 2019-11-13, release date: 2020-11-18, Last modification date: 2023-11-22)

• Primary citation: Imai, D.,Numoto, N.,Nakano, S.,Kakuta, H.,Ito, N.; Crystal structure of dimeric RXR-LBD complexed with full agonist NEt-3IB and TIF2 co-activator; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)