6KX6
Crystal structure of mouse Cryptochrome 1 in complex with KL101 compound
Summary for 6KX6
| Entry DOI | 10.2210/pdb6kx6/pdb |
| Descriptor | Cryptochrome-1, ~{N}-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl-benzamide (3 entities in total) |
| Functional Keywords | circadian clock protein |
| Biological source | Mus musculus (Mouse) |
| Total number of polymer chains | 2 |
| Total formula weight | 115498.47 |
| Authors | Miller, S.A.,Aikawa, Y.,Hirota, T. (deposition date: 2019-09-10, release date: 2020-04-01, Last modification date: 2023-11-22) |
| Primary citation | Miller, S.,Son, Y.L.,Aikawa, Y.,Makino, E.,Nagai, Y.,Srivastava, A.,Oshima, T.,Sugiyama, A.,Hara, A.,Abe, K.,Hirata, K.,Oishi, S.,Hagihara, S.,Sato, A.,Tama, F.,Itami, K.,Kay, S.A.,Hatori, M.,Hirota, T. Isoform-selective regulation of mammalian cryptochromes. Nat.Chem.Biol., 16:676-685, 2020 Cited by PubMed: 32231341DOI: 10.1038/s41589-020-0505-1 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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