6KJR

Functional and structural insights into the unusual oxyanion hole-like geometry in macrolactin acyltransferase selective for dicarboxylic acyl donors

Summary for 6KJR

Entry DOI	10.2210/pdb6kjr/pdb
Descriptor	Putative beta-lactamase, 4-[[(3~{E},5~{Z},8~{S},9~{E},11~{E},14~{S},16~{R},17~{Z},19~{E},24~{R})-24-methyl-14,16-bis(oxidanyl)-2-oxidanylidene-1-oxacyclotetracosa-3,5,9,11,17,19-hexaen-8-yl]oxy]-4-oxidanylidene-butanoic acid (3 entities in total)
Functional Keywords	acyltransferase, transferase
Biological source	Jeotgalibacillus marinus
Total number of polymer chains	1
Total formula weight	44726.02
Authors	Xiao, F.,Dong, S.,Feng, Y.,Li, W. (deposition date: 2019-07-23, release date: 2020-07-29, Last modification date: 2023-11-22)
Primary citation	Xiao, F.,Dong, S.,Liu, Y.,Feng, Y.,Li, H.,Yun, C.H.,Cui, Q.,Li, W. Structural Basis of Specificity for Carboxyl-Terminated Acyl Donors in a Bacterial Acyltransferase. J.Am.Chem.Soc., 142:16031-16038, 2020 Cited by PubMed: 32803979 DOI: 10.1021/jacs.0c07331 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.361 Å)

Structure validation