6KEA
crystal structure of MBP-tagged REV7-IpaB complex
Summary for 6KEA
Entry DOI | 10.2210/pdb6kea/pdb |
Descriptor | Maltose-binding periplasmic protein,LINKER,hREV7,LINKER,Invasin IpaB,hREV3 (2 entities in total) |
Functional Keywords | rev7, mad2b, mad2l2, shigella invasin ipab, cell cycle |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 4 |
Total formula weight | 275854.28 |
Authors | Wang, X.,Pernicone, N.,Pertz, L.,Hua, D.P.,Zhang, T.Q.,Listovsky, T.,Xie, W. (deposition date: 2019-07-04, release date: 2019-09-11, Last modification date: 2023-11-22) |
Primary citation | Wang, X.,Pernicone, N.,Pertz, L.,Hua, D.,Zhang, T.,Listovsky, T.,Xie, W. REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch. J.Biol.Chem., 294:15733-15742, 2019 Cited by PubMed: 31484720DOI: 10.1074/jbc.RA119.010123 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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