6KE5

Structure of CavAb in complex with Diltiazem and Amlodipine

Summary for 6KE5

Entry DOI	10.2210/pdb6ke5/pdb
Descriptor	Ion transport protein, [1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE, CALCIUM ION, ... (7 entities in total)
Functional Keywords	voltage gated ion channel, voltage-gated calcium channel, block, tetrameric, membrane protein
Biological source	Arcobacter butzleri RM4018
Total number of polymer chains	4
Total formula weight	135040.82
Authors	Tang, L. (deposition date: 2019-07-03, release date: 2019-10-23, Last modification date: 2024-03-27)
Primary citation	Tang, L.,Gamal El-Din, T.M.,Lenaeus, M.J.,Zheng, N.,Catterall, W.A. Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+Channel. Mol.Pharmacol., 96:485-492, 2019 Cited by PubMed: 31391290 DOI: 10.1124/mol.119.117531 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.803 Å)

Structure validation