6KDO
HIV-1 reverse transcriptase with Q151M/Y115F/F116Y/M184V/F160M:DNA:lamivudine 5'-triphosphate ternary complex
Summary for 6KDO
Entry DOI | 10.2210/pdb6kdo/pdb |
Related PRD ID | PRD_900003 |
Descriptor | HIV-1 reverse transcriptase p66 subunit, HIV-1 RT p51 subunit, DNA/RNA (38-MER), ... (7 entities in total) |
Functional Keywords | lamivudine 5'-triphosphate, hiv-1, hbv, reverse transcriptase, drug resistance, drug sensitivity, transferase-dna complex, replication, transferase/dna |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 6 |
Total formula weight | 256871.90 |
Authors | Yasutake, Y.,Hattori, S.I.,Tamura, N.,Maeda, K. (deposition date: 2019-07-02, release date: 2020-03-04, Last modification date: 2023-11-22) |
Primary citation | Yasutake, Y.,Hattori, S.I.,Tamura, N.,Matsuda, K.,Kohgo, S.,Maeda, K.,Mitsuya, H. Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10:3021-3021, 2020 Cited by PubMed: 32080249DOI: 10.1038/s41598-020-59775-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.573 Å) |
Structure validation
Download full validation report