6JEY
Covalent bond formation between ynone moiety of synthetic fatty acid and hPPARg-LBD
Summary for 6JEY
Entry DOI | 10.2210/pdb6jey/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, (9Z,12Z,15Z,18Z,21Z)-5-oxidanylidenetetracosa-9,12,15,18,21-pentaen-6-ynoic acid (3 entities in total) |
Functional Keywords | receptor, covalent ligand, ynone, oxo-fatty acid, nuclear protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 64004.57 |
Authors | Kojima, H.,Yamamoto, K.,Itoh, T. (deposition date: 2019-02-07, release date: 2020-02-12, Last modification date: 2023-11-22) |
Primary citation | Kojima, H.,Fujita, Y.,Takeuchi, R.,Ikebe, Y.,Ohashi, N.,Yamamoto, K.,Itoh, T. Cyclization Reaction-Based Turn-on Probe for Covalent Labeling of Target Proteins. Cell Chem Biol, 27:334-, 2020 Cited by PubMed: 31991094DOI: 10.1016/j.chembiol.2020.01.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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