6J7W

Crystal Structure of Human BCMA in complex with UniAb(TM) VH

Summary for 6J7W

• Entry DOI: 10.2210/pdb6j7w/pdb
• Descriptor: UniAb, Tumor necrosis factor receptor superfamily member 17 (3 entities in total)
• Functional Keywords: heavy chain antibodies, vh domains, domain antibodies, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 33889.46

Authors

Clarke, S.C.,Ma, B.,Trinklein, N.D.,Schellenberger, U.,Osborn, M.,Ouisse, L.,Boudreau, A.,Davison, L.,Harris, K.E.,Ugamraj, H.,Balasubramani, A.,Dang, K.,Jorgensen, B.,Ogana, H.,Pham, D.,Pratap, P.,Sankaran, P.,Anegon, I.,van Schooten, W.,Bruggemann, M.,Buelow, R.,Force Aldred, S. (deposition date: 2019-01-18, release date: 2019-02-06, Last modification date: 2023-11-22)

• Primary citation: Clarke, S.C.,Ma, B.,Trinklein, N.D.,Schellenberger, U.,Osborn, M.J.,Ouisse, L.H.,Boudreau, A.,Davison, L.M.,Harris, K.E.,Ugamraj, H.S.,Balasubramani, A.,Dang, K.H.,Jorgensen, B.,Ogana, H.A.N.,Pham, D.T.,Pratap, P.P.,Sankaran, P.,Anegon, I.,van Schooten, W.C.,Bruggemann, M.,Buelow, R.,Force Aldred, S.; Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies; Front Immunol, 9:3037-3037, 2018; PubMed: 30666250; DOI: 10.3389/fimmu.2018.03037

Experimental method

X-RAY DIFFRACTION (2.6 Å)