6HEB
Influenza A Virus N9 Neuraminidase complex with Oseltamivir (Tern).
Summary for 6HEB
Entry DOI | 10.2210/pdb6heb/pdb |
Descriptor | Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | complex, oseltamivir, tamiflu, neuraminidase, n9, influenza, virus, hydrolase, enzyme, inhibitor, gs4071 |
Biological source | Influenza A virus (strain A/Tern/Australia/G70C/1975 H11N9) |
Total number of polymer chains | 1 |
Total formula weight | 47049.03 |
Authors | Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F. (deposition date: 2018-08-20, release date: 2018-08-29, Last modification date: 2024-01-17) |
Primary citation | Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F. High Resolution Structures of Viral Neuraminidase with Drugs Bound in the Active Site. To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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