6GTW
Crystal structure of the FimH lectin domain from E.coli F18 in complex with trimannose
Summary for 6GTW
Entry DOI | 10.2210/pdb6gtw/pdb |
Descriptor | FimH protein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | type i pilus, catch-bond, cell adhesion, lectin, upec, infection, mannose |
Biological source | Escherichia coli F18+ |
Total number of polymer chains | 4 |
Total formula weight | 68912.41 |
Authors | Jakob, R.P.,Sauer, M.M.,Luber, T.,Canonica, F.,Navarra, G.,Ernst, B.,Unverzagt, C.,Maier, T.,Glockshuber, R. (deposition date: 2018-06-19, release date: 2019-01-16, Last modification date: 2024-10-16) |
Primary citation | Sauer, M.M.,Jakob, R.P.,Luber, T.,Canonica, F.,Navarra, G.,Ernst, B.,Unverzagt, C.,Maier, T.,Glockshuber, R. Binding of the Bacterial Adhesin FimH to Its Natural, Multivalent High-Mannose Type Glycan Targets. J.Am.Chem.Soc., 141:936-944, 2019 Cited by PubMed: 30543411DOI: 10.1021/jacs.8b10736 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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