6GF3
Tubulin-Jerantinine B acetate complex
Summary for 6GF3
Entry DOI | 10.2210/pdb6gf3/pdb |
Descriptor | Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Jerantinine B, ... (14 entities in total) |
Functional Keywords | cell cycle, tubulin fold, cytoskeleton, microtubule |
Biological source | Rattus norvegicus (Norway Rat) More |
Total number of polymer chains | 6 |
Total formula weight | 265125.67 |
Authors | Smedley, C.J.,Stanley, P.A.,Qazzaz, M.E.,Prota, A.E.,Olieric, N.,Collins, H.,Eastman, H.,Barrow, A.S.,Lim, K.-H.,Kam, T.-S.,Smith, B.J.,Duivenvoorden, H.M.,Parker, B.S.,Bradshaw, T.D.,Steinmetz, M.O.,Moses, J.E. (deposition date: 2018-04-29, release date: 2019-05-08, Last modification date: 2024-01-17) |
Primary citation | Smedley, C.J.,Stanley, P.A.,Qazzaz, M.E.,Prota, A.E.,Olieric, N.,Collins, H.,Eastman, H.,Barrow, A.S.,Lim, K.H.,Kam, T.S.,Smith, B.J.,Duivenvoorden, H.M.,Parker, B.S.,Bradshaw, T.D.,Steinmetz, M.O.,Moses, J.E. Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site. Sci Rep, 8:10617-10617, 2018 Cited by PubMed: 30006510DOI: 10.1038/s41598-018-28880-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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