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6GCH

STRUCTURE OF CHYMOTRYPSIN-*TRIFLUOROMETHYL KETONE INHIBITOR COMPLEXES. COMPARISON OF SLOWLY AND RAPIDLY EQUILIBRATING INHIBITORS

Summary for 6GCH
Entry DOI10.2210/pdb6gch/pdb
DescriptorGAMMA-CHYMOTRYPSIN A, 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE), ... (5 entities in total)
Functional Keywordshydrolase (serine proteinase)
Biological sourceBos taurus (cattle)
More
Cellular locationSecreted, extracellular space: P00766 P00766 P00766
Total number of polymer chains3
Total formula weight25521.79
Authors
Brady, K.,Wei, A.,Ringe, D.,Abeles, R.H. (deposition date: 1990-04-06, release date: 1990-10-15, Last modification date: 2011-07-13)
Primary citationBrady, K.,Wei, A.Z.,Ringe, D.,Abeles, R.H.
Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors.
Biochemistry, 29:7600-7607, 1990
Cited by
PubMed: 2271520
DOI: 10.1021/bi00485a009
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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