6G2M
Crystal structure of human mitochondrial 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PAU
Summary for 6G2M
Entry DOI | 10.2210/pdb6g2m/pdb |
Related | 6G22 6G2L 6G2N |
Descriptor | 5'(3')-deoxyribonucleotidase, mitochondrial, BETA-MERCAPTOETHANOL, GLYCEROL, ... (8 entities in total) |
Functional Keywords | 5'-nucleotidase, dephosphorylation, phosphorylation, had-like, mitochondria, hydrolase-hydrolase inhibitor complex, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 24267.75 |
Authors | Pachl, P.,Rezacova, P.,Brynda, J. (deposition date: 2018-03-23, release date: 2018-07-11, Last modification date: 2024-01-17) |
Primary citation | Pachl, P.,Simak, O.,Budesinsky, M.,Brynda, J.,Rosenberg, I.,Rezacova, P. Structure-based optimization of bisphosphonate nucleoside inhibitors of human 5'(3')-deoxyribonucleotidases Eur.J.Org.Chem., 2018 Cited by DOI: 10.1002/ejoc.201800515PDB entries with the same primary citation |
Experimental method |
Structure validation
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