6G0H

BRD4 (BD1) in complex with APSC-derived ligands (e.g. SSLH01 a sulfasalazine derivate)

Summary for 6G0H

Entry DOI	10.2210/pdb6g0h/pdb
Descriptor	Bromodomain-containing protein 4, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywords	brd4, transcription
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	15652.99
Authors	Humbeck, L.,Pretzel, J. (deposition date: 2018-03-18, release date: 2020-01-08, Last modification date: 2024-01-17)
Primary citation	Humbeck, L.,Pretzel, J.,Spitzer, S.,Koch, O. Discovery of an Unexpected Similarity in Ligand Binding Between BRD4 and PPARgamma Chemrxiv, 2019 Cited by DOI: 10.26434/chemrxiv.11472618 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.907 Å)

Structure validation