6FDI
Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-226
Summary for 6FDI
Entry DOI | 10.2210/pdb6fdi/pdb |
Descriptor | cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ... (9 entities in total) |
Functional Keywords | phosphodiesterase, hydrolase, camp hydrolysis, alternative splicing |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 174657.86 |
Authors | Singh, A.K.,Brown, D.G. (deposition date: 2017-12-24, release date: 2019-04-10, Last modification date: 2024-01-17) |
Primary citation | Salado, I.G.,Moreno, C.,Sakaine, G.,Singh, A.K.,Blaazer, A.R.,Siderius, M.,Matheeussen, A.,Gul, S.,Maes, L.,Leurs, R.,Brown, D.G.,Augustyns, K. hPDE4D2 structure with inhibitor NPD-226 To be published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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