6DWM
Structure of Human Cytochrome P450 1A1 with Bergamottin
Summary for 6DWM
Entry DOI | 10.2210/pdb6dwm/pdb |
Descriptor | Cytochrome P450 1A1, PROTOPORPHYRIN IX CONTAINING FE, 4-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-7H-furo[3,2-g][1]benzopyran-7-one, ... (6 entities in total) |
Functional Keywords | ligand, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 229010.10 |
Authors | Bart, A.G.,Scott, E.E. (deposition date: 2018-06-26, release date: 2018-10-03, Last modification date: 2023-10-11) |
Primary citation | Bart, A.G.,Scott, E.E. Structures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands. J. Biol. Chem., 293:19201-19210, 2018 Cited by PubMed: 30254074DOI: 10.1074/jbc.RA118.005588 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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