6CYW

Structure of sphingomyelin in complex with mouse CD1d

Summary for 6CYW

Entry DOI	10.2210/pdb6cyw/pdb
Descriptor	Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	glycolipid-antigen presentation, mhc-fold, ig-fold, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	2
Total formula weight	45974.07
Authors	Zajonc, D.M.,Wang, J. (deposition date: 2018-04-06, release date: 2019-04-10, Last modification date: 2023-10-04)
Primary citation	Melum, E.,Jiang, X.,Baker, K.D.,Macedo, M.F.,Fritsch, J.,Dowds, C.M.,Wang, J.,Pharo, A.,Kaser, A.,Tan, C.,Pereira, C.S.,Kelly, S.L.,Duan, J.,Karlsen, T.H.,Exley, M.A.,Schutze, S.,Zajonc, D.M.,Merrill, A.H.,Schuchman, E.H.,Zeissig, S.,Blumberg, R.S. Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. Nat.Immunol., 20:1644-1655, 2019 Cited by PubMed: 31636468 DOI: 10.1038/s41590-019-0504-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation