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6CX7

Structure of alpha-GSA[12,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR

Summary for 6CX7
Entry DOI10.2210/pdb6cx7/pdb
DescriptorChimeric T cell antigen receptor alpha chain Va14,Va24,Ja18, Chimeric T cell antigen receptor beta chain Vb8.2, vb11, Antigen-presenting glycoprotein CD1d1, ... (9 entities in total)
Functional Keywordsimmune system, antigen-presentation, tcr, mhc-fold
Biological sourceMus musculus (Mouse)
More
Total number of polymer chains4
Total formula weight96470.91
Authors
Wang, J.,Zajonc, D. (deposition date: 2018-04-02, release date: 2019-04-10, Last modification date: 2023-10-04)
Primary citationWang, J.,Guillaume, J.,Janssens, J.,Remesh, S.G.,Ying, G.,Bitra, A.,Van Calenbergh, S.,Zajonc, D.M.
A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294:14345-14356, 2019
Cited by
PubMed: 31391251
DOI: 10.1074/jbc.RA119.009963
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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