6CNJ
Structure of the 2alpha3beta stiochiometry of the human Alpha4Beta2 nicotinic receptor
Summary for 6CNJ
Entry DOI | 10.2210/pdb6cnj/pdb |
EMDB information | 7535 |
Descriptor | Neuronal acetylcholine receptor subunit alpha-4, Neuronal acetylcholine receptor subunit beta-2, IgG1 Kappa Light Chain, ... (9 entities in total) |
Functional Keywords | ligand-gated ion channel, acetylcholine receptor, cys-loop receptor, membrane protein, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 11 |
Total formula weight | 470110.87 |
Authors | Walsh Jr, R.M.,Roh, S.H.,Gharpure, A.,Morales-Perez, C.L.,Teng, J.,Hibbs, R.E. (deposition date: 2018-03-08, release date: 2018-05-02, Last modification date: 2020-07-29) |
Primary citation | Walsh, R.M.,Roh, S.H.,Gharpure, A.,Morales-Perez, C.L.,Teng, J.,Hibbs, R.E. Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor. Nature, 557:261-265, 2018 Cited by PubMed: 29720657DOI: 10.1038/s41586-018-0081-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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