6BTO

BMP1 complexed with (2~{S})-2-[[(1~{R},3~{S},4~{S})-2-[(2~{R})-2-[2-(oxidanylamino)-2-oxidanylidene-ethyl]heptanoyl]-2-azabicyclo[2.2.1]heptan-3-yl]carbonylamino]-2-phenyl-ethanoic acid

Summary for 6BTO

Entry DOI	10.2210/pdb6bto/pdb
Descriptor	Bone morphogenetic protein 1, THIOCYANATE ION, ZINC ION, ... (6 entities in total)
Functional Keywords	endopeptidase, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	47036.52
Authors	Gampe, R.,Shewchuk, L. (deposition date: 2017-12-07, release date: 2018-08-08, Last modification date: 2019-04-24)
Primary citation	Kallander, L.S.,Washburn, D.,Hilfiker, M.A.,Eidam, H.S.,Lawhorn, B.G.,Prendergast, J.,Fox, R.,Dowdell, S.,Manns, S.,Hoang, T.,Zhao, S.,Ye, G.,Hammond, M.,Holt, D.A.,Roethke, T.,Hong, X.,Reid, R.A.,Gampe, R.,Zhang, H.,Diaz, E.,Rendina, A.R.,Quinn, A.M.,Willette, B. Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1. ACS Med Chem Lett, 9:736-740, 2018 Cited by PubMed: 30034610 DOI: 10.1021/acsmedchemlett.8b00173 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation