6ARN
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-methoxyphenyl beta-galactoside (OMPG)
Summary for 6ARN
| Entry DOI | 10.2210/pdb6arn/pdb |
| Descriptor | Putative Fml fimbrial adhesin FmlD, 2-methoxyphenyl beta-D-galactopyranoside, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | fimbrial adhesin, lectin, bacterial adhesion, sugar binding protein |
| Biological source | Escherichia coli |
| Total number of polymer chains | 2 |
| Total formula weight | 36508.79 |
| Authors | Kalas, V.,Hultgren, S.J. (deposition date: 2017-08-22, release date: 2018-02-28, Last modification date: 2023-10-04) |
| Primary citation | Kalas, V.,Hibbing, M.E.,Maddirala, A.R.,Chugani, R.,Pinkner, J.S.,Mydock-McGrane, L.K.,Conover, M.S.,Janetka, J.W.,Hultgren, S.J. Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115:E2819-E2828, 2018 Cited by PubMed: 29507247DOI: 10.1073/pnas.1720140115 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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