Structure of Nephrin/MAGI1 complex

Summary for 5ZYS

DescriptorMembrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Nephrin (3 entities in total)
Functional Keywordsslit diaphragm, nephrotic syndrome, magi1- nephrin complex, cell adhesion
Biological sourceMus musculus (Mouse)
Total number of polymer chains2
Total molecular weight11698.37
Weng, Z.F.,Shng, Y.,Zhu, J.W.,Zhang, R.G. (deposition date: 2018-05-28, release date: 2019-01-23)
Primary citation
Weng, Z.,Shang, Y.,Ji, Z.,Ye, F.,Lin, L.,Zhang, R.,Zhu, J.
Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling.
J. Am. Soc. Nephrol., 29:2362-2371, 2018
PubMed: 30006415 (PDB entries with the same primary citation)
DOI: 10.1681/ASN.2017121275
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.187200 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report