Summary for 5ZYA
| Entry DOI | 10.2210/pdb5zya/pdb |
| EMDB information | 6915 |
| Descriptor | Splicing factor 3B subunit 5, Splicing factor 3B subunit 1, PHD finger-like domain-containing protein 5A, ... (7 entities in total) |
| Functional Keywords | splicing modulator, sf3b sub-complex, splicing |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 302995.11 |
| Authors | Finci, L.I.,Larsen, N.A. (deposition date: 2018-05-23, release date: 2018-06-20, Last modification date: 2024-03-27) |
| Primary citation | Finci, L.I.,Zhang, X.,Huang, X.,Zhou, Q.,Tsai, J.,Teng, T.,Agrawal, A.,Chan, B.,Irwin, S.,Karr, C.,Cook, A.,Zhu, P.,Reynolds, D.,Smith, P.G.,Fekkes, P.,Buonamici, S.,Larsen, N.A. The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action Genes Dev., 32:309-320, 2018 Cited by PubMed: 29491137DOI: 10.1101/gad.311043.117 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.95 Å) |
Structure validation
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