5ZXH

The structure of MT189-tubulin complex

Summary for 5ZXH

• Entry DOI: 10.2210/pdb5zxh/pdb
• Descriptor: Tubulin alpha-1B chain, 2-(6-fluoro-3-{[(4-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyridin-2-yl)phenol, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total)
• Functional Keywords: tubulin complex, structural protein
• Biological source: Sus scrofa (Pig); More
• Total number of polymer chains: 6
• Total formula weight: 265065.44

Authors

Li, Z.P.,Wang, Y.X.,Meng, T.,Yang, J.L.,Chen, Q. (deposition date: 2018-05-21, release date: 2019-05-22, Last modification date: 2024-03-27)

• Primary citation: Li, Z.P.,Ma, L.L.,Wu, C.Y.,Meng, T.,Ma, L.P.,Zheng, W.,Yu, Y.,Chen, Q.,Yang, J.L.,Shen, J.G.; The Structure of MT189-Tubulin Complex Provides Insights into Drug Design; Lett.Drug Des.Discovery, 2019; DOI: 10.2174/1570180816666181122122655

Experimental method

X-RAY DIFFRACTION (2.8 Å)