5ZWR

Structural Basis for the Enantioselectivity of Est-Y29 toward (S)-ketoprofen

Summary for 5ZWR

DescriptorEst-Y29, GLYCEROL, (2S)-2-[3-(benzenecarbonyl)phenyl]propanoic acid, ... (4 entities in total)
Functional Keywordsest-y29, esterase, ketoprofen, 2-(3-benzoylphenyl)-propionic acid, hydrolase
Biological sourcemetagenome
Total number of polymer chains2
Total molecular weight89109.55
Authors
Ngo, D.T.,Oh, C.,Park, K.,Nguyen, L.,Byun, H.M.,Kim, S.,Yoon, S.,Ryu, Y.,Ryu, B.H.,Kim, T.D.,Kim, K.K. (deposition date: 2018-05-16, release date: 2019-03-13)
Primary citation
Ngo, T.D.,Oh, C.,Mizar, P.,Baek, M.,Park, K.,Nguyen, L.,Byeon, H.,Yoon, S.,Ryu, B.H.,Kim, T.D.,Yang, J.W.,Seok, C.,Lee, S.S.,Kim, K.K.
Structural Basis for the Enantioselectivity of Esterase Est-Y29 toward (S)-Ketoprofen
Acs Catalysis, 9:755-767, 2019
DOI: 10.1021/acscatal.8b02797
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.69 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1784 0.1% 1.4% 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5zwr
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Molmil generated image of 5zwr
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Molmil generated image of 5zwr
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More Biological unit images

Molmil generated image of 5zwr
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Molmil generated image of 5zwr
rotated about x axis by 90°
Molmil generated image of 5zwr
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (5zwr.pdb1.gz [575.78 KB])