5ZVK
Crystal Structure of the Human Coronavirus MERS HR1 motif in complex with pan-CoVs inhibitor EK1
Summary for 5ZVK
Entry DOI | 10.2210/pdb5zvk/pdb |
Related | 5zuv |
Descriptor | Human Coronavirus MERS HR1 motif, pan-CoV inhibitory peptide EK1 (2 entities in total) |
Functional Keywords | mers, spike protein, s2 domain, hr1 motif, pan-coronavirus, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Middle East respiratory syndrome-related coronavirus (MERS coronavirus, MERS-CoV) More |
Total number of polymer chains | 6 |
Total formula weight | 40455.20 |
Authors | Yan, L.,Yang, B.,Wilson, I.A. (deposition date: 2018-05-11, release date: 2019-04-10, Last modification date: 2023-11-22) |
Primary citation | Xia, S.,Yan, L.,Xu, W.,Agrawal, A.S.,Algaissi, A.,Tseng, C.K.,Wang, Q.,Du, L.,Tan, W.,Wilson, I.A.,Jiang, S.,Yang, B.,Lu, L. A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Sci Adv, 5:eaav4580-eaav4580, 2019 Cited by PubMed: 30989115DOI: 10.1126/sciadv.aav4580 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.31 Å) |
Structure validation
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