5ZTO

Crystal structure of EGFR 696-1022 T790M/C797S in complex with D3003

Summary for 5ZTO

• Entry DOI: 10.2210/pdb5zto/pdb
• Descriptor: Epidermal growth factor receptor, N-{trans-4-[3-(2-chlorophenyl)-7-{[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]cyclohexyl}propanamide, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: egfr, t790m/c797s, inhibitor, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 38287.17

Authors

Zhu, S.J.,Yun, C.H. (deposition date: 2018-05-04, release date: 2019-06-12, Last modification date: 2023-11-22)

• Primary citation: Zhu, S.J.,Yun, C.H.; Crystal structure of EGFR 696-1022 T790M/C797S in complex with D3003; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.649 Å)