5ZM5
Crystal structure of human ORP1-ORD in complex with cholesterol at 2.6 A resolution
Summary for 5ZM5
Entry DOI | 10.2210/pdb5zm5/pdb |
Descriptor | Oxysterol-binding protein-related protein 1, CHOLESTEROL (3 entities in total) |
Functional Keywords | transporter, complex, lipid transport |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 50367.67 |
Authors | |
Primary citation | Dong, J.,Du, X.,Wang, H.,Wang, J.,Lu, C.,Chen, X.,Zhu, Z.,Luo, Z.,Yu, L.,Brown, A.J.,Yang, H.,Wu, J.W. Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2. Nat Commun, 10:829-829, 2019 Cited by PubMed: 30783101DOI: 10.1038/s41467-019-08791-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report