5ZKO

Crystal structure of the CRTC2-CREB-CRE complex

Summary for 5ZKO

• Entry DOI: 10.2210/pdb5zko/pdb
• Descriptor: Cyclic AMP-responsive element-binding protein 1, DNA (5'-D(*CP*TP*TP*GP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*CP*AP*AP*G)-3'), CREB-regulated transcription coactivator 2 (3 entities in total)
• Functional Keywords: transcription factor, coactivator, creb, cre, crtc, transcription, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 43569.81

Authors

Xiang, S.,Zhai, L.,Valecia-Swain, J. (deposition date: 2018-03-24, release date: 2018-06-20, Last modification date: 2023-11-22)

• Primary citation: Song, Y.,Zhai, L.,Valencia Swain, J.,Chen, Y.,Wang, P.,Chen, L.,Liu, Y.,Xiang, S.; Structural Insights into the CRTC2-CREB Complex Assembly on CRE.; J. Mol. Biol., 430:1926-1939, 2018; PubMed: 29733854; DOI: 10.1016/j.jmb.2018.04.038

Experimental method

X-RAY DIFFRACTION (3.05 Å)