5ZIA

Crystal structure of human anti-tau antibody CBTAU-24.1 in complex with its phosphorylated tau peptide

5ZIA の概要

• エントリーDOI: 10.2210/pdb5zia/pdb
• 分子名称: Heavy chain of CBTAU-24.1 antibody, Light chain (kappa) of CBTAU-24.1 antibody, phosphorylated tau peptide, ... (4 entities in total)
• 機能のキーワード: antibody, tau protein, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 18
• 化学式量合計: 297450.09

構造登録者

Zhang, H.,Wilson, I.A. (登録日: 2018-03-14, 公開日: 2018-10-31, 最終更新日: 2023-11-22)

• 主引用文献: Zhang, H.,Zhu, X.,Pascual, G.,Wadia, J.S.,Keogh, E.,Hoozemans, J.J.,Siregar, B.,Inganas, H.,Stoop, E.J.M.,Goudsmit, J.,Apetri, A.,Koudstaal, W.,Wilson, I.A.; Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody.; Structure, 26:1626-1634.e4, 2018; PubMed: 30318466; DOI: 10.1016/j.str.2018.08.012

実験手法

X-RAY DIFFRACTION (2.603 Å)