5ZGI

Crystal structure of NDM-1 at pH6.5 (Succinate) with 1 molecule per asymmetric unit

Summary for 5ZGI

• Entry DOI: 10.2210/pdb5zgi/pdb
• Related: 5XP6
• Descriptor: Metallo-beta-lactamase type 2, ZINC ION, HYDROXIDE ION, ... (6 entities in total)
• Functional Keywords: ndm-1, metallo-beta-lactamase, antibiotic resistent, conformational change, antibiotic, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 26083.94

Authors

Zhang, H.,Hao, Q. (deposition date: 2018-03-09, release date: 2018-08-22, Last modification date: 2023-11-22)

• Primary citation: Zhang, H.,Ma, G.,Zhu, Y.,Zeng, L.,Ahmad, A.,Wang, C.,Pang, B.,Fang, H.,Zhao, L.,Hao, Q.; Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1.; Antimicrob. Agents Chemother., 62:-, 2018; PubMed: 30150473; DOI: 10.1128/AAC.01579-18

Experimental method

X-RAY DIFFRACTION (0.98 Å)