5ZEF

Crystal structure of Entamoeba histolytica Arginase in complex with L- Norvaline at 2.01 A

Summary for 5ZEF

Entry DOI	10.2210/pdb5zef/pdb
Descriptor	Arginase, NORVALINE, MANGANESE (II) ION, ... (6 entities in total)
Functional Keywords	entamoeba histolytica, metalloenzyme, inhibition, hydrolase
Biological source	Entamoeba histolytica
Total number of polymer chains	2
Total formula weight	70416.18
Authors	Malik, A.,Dalal, V.,Ankri, S.,Tomar, S. (deposition date: 2018-02-27, release date: 2019-06-26, Last modification date: 2023-11-22)
Primary citation	Malik, A.,Dalal, V.,Ankri, S.,Tomar, S. Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules. Febs J., 286:4135-4155, 2019 Cited by PubMed: 31199070 DOI: 10.1111/febs.14960 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.01 Å)

Structure validation