5ZEE

Crystal structure of Entamoeba histolytica Arginase in complex with N(omega)-hydroxy-L-arginine (NOHA) at 1.74 A

5ZEE の概要

• エントリーDOI: 10.2210/pdb5zee/pdb
• 分子名称: Arginase, N-OMEGA-HYDROXY-L-ARGININE, MANGANESE (II) ION, ... (5 entities in total)
• 機能のキーワード: metalloenzyme, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Entamoeba histolytica
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70502.24

構造登録者

Malik, A.,Dalal, V.,Ankri, S.,Tomar, S. (登録日: 2018-02-27, 公開日: 2019-06-26, 最終更新日: 2023-11-22)

• 主引用文献: Malik, A.,Dalal, V.,Ankri, S.,Tomar, S.; Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.; Febs J., 286:4135-4155, 2019; PubMed: 31199070; DOI: 10.1111/febs.14960

実験手法

X-RAY DIFFRACTION (1.74 Å)