5ZED

Crystal structure of Kluyveromyces polyspora ADH (KpADH) mutant (E214V/T215S)

5ZED の概要

• エントリーDOI: 10.2210/pdb5zed/pdb
• 分子名称: Uncharacterized protein ADH, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• 機能のキーワード: alcohol dehydrogenase(kpadh), nadph, isomerase
• 由来する生物種: Vanderwaltozyma polyspora DSM 70294 (Kluyveromyces polysporus)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79297.08

構造登録者

Wang, Y.,Zhou, J.Y.,Hou, X.D.,Xu, G.C.,Wu, L.,Rao, Y.J.,ZHou, J.H.,Ni, Y. (登録日: 2018-02-27, 公開日: 2019-01-02, 最終更新日: 2023-11-22)

• 主引用文献: Zhou, J.Y.,Wang, Y.,Xu, G.C.,Wu, L.,Han, R.Z.,Schwaneberg, U.,Rao, Y.J.,Zhao, Y.L.,Zhou, J.H.,Ni, Y.; Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones.; J. Am. Chem. Soc., 140:12645-12654, 2018; PubMed: 30247889; DOI: 10.1021/jacs.8b08640

実験手法

X-RAY DIFFRACTION (2.199 Å)