5Z9P

Bacterial GyrB ATPase domain in complex with a chemical fragment

Summary for 5Z9P

Entry DOI	10.2210/pdb5z9p/pdb
Descriptor	DNA gyrase subunit B, 1H-benzimidazol-2-amine, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	dna topoisomerase, antibacterial, drug target, fragment-base lead discovery, isomerase
Biological source	Staphylococcus aureus
Total number of polymer chains	2
Total formula weight	45142.95
Authors	Huang, X.,Zhou, H. (deposition date: 2018-02-04, release date: 2018-12-12, Last modification date: 2023-11-22)
Primary citation	Huang, X.,Guo, J.,Liu, Q.,Gu, Q.,Xu, J.,Zhou, H. Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes Medchemcomm, 9:1619-1629, 2018 Cited by PubMed: 30429968 DOI: 10.1039/c8md00148k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation