5Z8S

Human Mitochondrial ferritin mutant - C102A/C130A/E27C/E61C/E62C

Summary for 5Z8S

• Entry DOI: 10.2210/pdb5z8s/pdb
• Descriptor: Ferritin, mitochondrial, GOLD ION (3 entities in total)
• Functional Keywords: mitochondrail ferritin, gold, cysteine, metal binding protein, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 21200.21

Authors

Zang, J.,Zheng, B.,Zhao, G. (deposition date: 2018-02-01, release date: 2019-02-06, Last modification date: 2024-03-27)

Primary citation

Zang, J.,Zheng, B.,Zhang, X.,Arosio, P.,Zhao, G.
Design and site-directed compartmentalization of gold nanoclusters within the intrasubunit interfaces of ferritin nanocage.
J Nanobiotechnology, 17:79-79, 2019

PubMed Abstract: Protein nanocages have emerged as popular nanocarriers for either drug delivery or biotemplates for the preparation of nanomaterials. However, only three interfaces, namely exterior surface, intersubunit and inner cavity, have been used as reaction sites for the above purposes with all known protein nanocages. On the other hand, how to control the site of Au NCs formed within a targeted protein template while maintaining the functionality of protein itself remains challenging.

PubMed: 31277668
DOI: 10.1186/s12951-019-0512-0

Experimental method

X-RAY DIFFRACTION (1.973 Å)